Wall Street regains some ground after virus pullback


* S&P tech sector lead gains

* Twitter down 0.6% after CEO Dorsey steps down

* Indexes up: Dow 0.39%, S&P 1.10%, Nasdaq 1.50%

By Ambar Warrick and Sinéad Carew

Nov 29 (Reuters) - Wall Street regained some of Friday's losses on Monday, with the technology sector leading the charge and investors appearing to be somewhat reassured by U.S. President Joe Biden's comments about the Omicron virus variant.

The S&P and the Dow suffered their biggest one-day percentage declines in months in Friday's holiday-shortened session as investors worried that the latest variant of the COVID-19 virus would cause economic disruption.

But Biden said on Monday that Omicron-related lockdowns were off the table for now, though he noted the variant was a cause for concern but not for panic as he urged Americans to get vaccinated and wear masks indoors.

Those comments and indications from drug companies that they are taking the variant seriously were reassuring for investors, who had been anxious about the potential for further COVID restrictions, according to Carol Schleif, deputy chief investment officer for the BMO family office in Minneapolis.

"It's not like the start of the pandemic all over again," said Schleif, who also noted that after Friday's knee-jerk reaction, investors have been trained this year to buy the dip. "People are willing to just take a deep breath and try to reassess, be a little more patient."

By 2:59 p.m. ET, the Dow Jones Industrial Average .DJI rose 283.43 points, or 0.81%, to 35,182.77, the S&P 500 .SPX gained 68.99 points, or 1.50%, to 4,663.61 and the Nasdaq Composite .IXIC added 306.63 points, or 1.98%, to 15,798.29.

Among the S&P's 11 major sectors, technology .SPLRCT led with an almost 3% gain, followed by real estate .SPLRCR and consumer discretionary .SPLRCD .

Gains in Amazon.com AMZN.O and Tesla Inc TSLA.O helped boost the S&P with investors viewing Friday's losses as a cue for bargain-hunting on high-value tech names.

"People are looking at it as a little bit of a sale on Friday and an opportunity to get into some areas of the market that got hit hard," said Robert Pavlik, senior portfolio manager at Dakota Wealth Management.

Twitter Inc TWTR.N reversed early gains and traded down 1.7% after the social media firm said CEO Jack Dorsey will step down and be succeeded by Chief Technology Officer Parag Agrawal. The move ends Dorsey's run as CEO of two major technology companies, the second being digital payments firm Square Inc SQ.N .

Square's shares were up 0.8%.

The Dow .DJI was up solidly but underperformed its peers under pressure from Merck & Co Inc MRK.N , which was down more than 5.8%. It extended losses from Friday, when updated data from a study of its experimental COVID-19 pill showed lower efficacy in reducing risk of hospitalization and deaths than previously reported.

Among other stocks, casino operators Wynn Resorts WYNN.O and MGM Resorts International MGM.N fell 3% and 0.7%, respectively, tracking losses in their Macau units, which were rattled by arrests over alleged links to cross-border gambling and money laundering.

Advanced Micro Devices AMD.O rose 3.5% following a report that electric-car maker Tesla has started using a new AMD chip in Model Y vehicles in China.

Tesla's shares gained 4% after a report that chief Elon Musk urged employees to reduce the cost of vehicle deliveries.

The S&P's biggest boost was from Apple Inc AAPL.O , which gained 2% after HSBC raised its price target on the iPhone maker's stock.

Advancing issues outnumbered declining ones on the NYSE by a 1.43-to-1 ratio; on Nasdaq, a 1.14-to-1 ratio favored decliners.

The S&P 500 posted 12 new 52-week highs and 19 new lows; the Nasdaq Composite recorded 34 new highs and 292 new lows.
Reporting By Sinéad Carew; Editing by Dan Grebler

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